| Aging of the autonomic nervous system and possible improvements in autonomic activity using somatic afferent stimulation. | |
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MedLine Citation:
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PMID: 20590828 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There are significant age-related changes in autonomic nervous system function that are responsible for an impaired ability to adapt to environmental or intrinsic visceral stimuli in the elderly. We review data on changes in autonomic nervous system regulation of cardiovascular and urinary function, as well as data on strategies to improve function. There are data showing alterations in peripheral and central autonomic nerve activity, and decreases in neurotransmitter receptor action that lead to diminished autonomic reactivity (e.g. blood pressure and cerebral blood flow regulation) and poorly coordinated autonomic discharge (e.g. bladder function). Simple strategies for autonomic function improvement and increasing cortical blood flow include walking and somatic afferent stimulation (e.g. stroking skin or acupuncture) to increase sympathetic, parasympathetic and central cholinergic activity. |
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Authors:
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Harumi Hotta; Sae Uchida |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Geriatrics & gerontology international Volume: 10 Suppl 1 ISSN: 1447-0594 ISO Abbreviation: Geriatr Gerontol Int Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-01 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101135738 Medline TA: Geriatr Gerontol Int Country: Japan |
Other Details:
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Languages: eng Pagination: S127-36 Citation Subset: IM |
Affiliation:
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Department of the Autonomic Nervous System, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan. hhotta@tmig.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aging
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physiology* Animals Anoxia / physiopathology Autonomic Nervous System / physiology* Baroreflex / physiology Blood Pressure / physiology Brain / blood supply Cardiovascular Diseases / physiopathology Epinephrine / secretion Humans Muscle Contraction / physiology Norepinephrine / analysis Receptors, Catecholamine / physiology Regional Blood Flow / physiology Sympathetic Nervous System / physiology Urinary Bladder / physiology Urination / physiology |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Catecholamine; 51-41-2/Norepinephrine; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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