| Aging Impact on Thoracic Aorta 3D Morphometry in Intermediate-Risk Subjects: Looking Beyond Coronary Arteries with Non-Contrast Cardiac CT. | |
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MedLine Citation:
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PMID: 22173558 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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An increasing number of intermediate risk asymptomatic subjects benefit from measures of atherosclerosis burden like coronary artery calcification studies with non-contrast heart computed tomography (CT). However, additional information can be derived from these studies, looking beyond the coronary arteries and without exposing the patients to further radiation. We report a semi-automatic method that objectively assesses ascending, arch and descending aorta dimension and shape from non-contrast CT datasets to investigate the effect of aging on thoracic aorta geometry. First, the segmentation process identifies the vessel centerline coordinates following a toroidal path for the curvilinear portion and axial planes for descending aorta. Then, reconstructing oblique planes orthogonal to the centerline direction, it iteratively fits circles inside the vessel cross-section. Finally, regional thoracic aorta dimensions (diameter, volume and length) and shape (vessel curvature and tortuosity) are calculated. A population of 200 normotensive men was recruited. Length, mean diameter and volume differed by 1.2 cm, 0.13 cm and 21 cm(3) per decade of life, respectively. Aortic shape uncoiled with aging, reducing its tortuosity and increasing its radius of curvature. The arch was the most affected segment. In conclusion, non-contrast cardiac CT imaging can be successfully employed to assess thoracic aorta 3D morphometry. |
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Authors:
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Damian Craiem; Gilles Chironi; Alban Redheuil; Mariano Casciaro; Elie Mousseaux; Alain Simon; Ricardo L Armentano |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-16 |
Journal Detail:
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Title: Annals of biomedical engineering Volume: - ISSN: 1521-6047 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0361512 Medline TA: Ann Biomed Eng Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Favaloro University, Av. Belgrano 1723, CP 1093, Buenos Aires, Argentina, dcraiem@favaloro.edu.ar. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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