Document Detail

Aggressive mixed type endometrial carcinoma in a young woman with rapid progression and fatal outcome.
MedLine Citation:
PMID:  17639438     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Endometrial carcinoma in young ages is uncommon and tends to be a well differentiated endometrioid type and has an excellent prognosis. Nevertheless, in this report mixed type endometrial cancer including serous, clear cell and endometrioid components in a young patient with rapid progression and fatal outcome is presented. CASE: A 26-year-old virgin female was admitted with menometrohagia lasting for 9 months, leading to severe anemia. Transabdominal ultrasonography demonstrated 30 x 27 mm intramural mass consistent with leiomyoma in uterine corpus posterior. The patient did not permit any vaginal intervention including endometrial sampling, therefore laparotomy was decided. Mixed type endometrial carcinoma was diagnosed and she was treated with comprehensive surgery plus adjuvant chemotherapy. After 7 months of surgery she deceased. CONCLUSION: We suggest that persistent uterine bleeding associated with severe anemia should be evaluated for malignancy even in young women to avoid delay in diagnosis. Imaging studies especially magnetic resonance imaging may be helpful when endometrial sampling cannot be done.
Elif Aylin Taşkin; Salih Taşkin; Bülent Berker; Ebru Erol; Ilkkan Dünder; Feride Söylemez
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-17
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  277     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-16     Completed Date:  2008-09-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  71-3     Citation Subset:  IM    
Department of Obstetric and Gynecology, Ankara University Faculty of Medicine, Cebeci, Ankara, Turkey.
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MeSH Terms
Anemia / etiology
Chemotherapy, Adjuvant
Endometrial Neoplasms / pathology*,  therapy
Fatal Outcome
Menorrhagia / etiology
Mixed Tumor, Malignant / pathology*,  therapy
Neoplasm Invasiveness
Neoplasm Metastasis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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