Document Detail


Aggressive and devastating neuropathy: the consequence of untreated slow-onset type 1 diabetes.
MedLine Citation:
PMID:  20663807     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Though type 1 diabetes (T1D) is described to be a disease of acute onset, there is strong evidence for a period of subclinical hyperglycaemia leading up to diagnosis. We describe two clinical cases with a prolonged and insidious onset of T1D, where neurological complications were present at the time of diagnosis. In both, there was an initial rapid and debilitating progression in neurological as well as other microvascular complications, but with a subsequent stabilization in complications over the next few years. These rare and unusual cases illustrate the variable nature of the natural history of T1D as well as its microvascular complications.
Authors:
P Narendran; S J Creely; A Syed; S Tesfaye; J Winer; B M Singh
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Publication Detail:
Type:  Journal Article     Date:  2010-07-27
Journal Detail:
Title:  QJM : monthly journal of the Association of Physicians     Volume:  104     ISSN:  1460-2393     ISO Abbreviation:  QJM     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9438285     Medline TA:  QJM     Country:  England    
Other Details:
Languages:  eng     Pagination:  523-6     Citation Subset:  IM    
Affiliation:
Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. p.narendran@bham.ac.uk.
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