Document Detail

Aggressive cardiac involvement in systemic lupus erythematosus: a case report and a comprehensive literature review.
MedLine Citation:
PMID:  21350606     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of lupus and used over 100 journals to identify the key points in pathology, diagnosis, and treatment. Results. We have shown that cardiac lupus can be rapidly progressive and, unless treated early, can have severe consequences. The predominant pathologies are immune complex and accelerated atherosclerosis drive. Treatment comprised of high-level immunosuppression.
Reza Ashrafi; Pankaj Garg; Ewan McKay; John Gosney; Som Chuah; Gershan Davis
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Publication Detail:
Type:  Journal Article     Date:  2011-02-15
Journal Detail:
Title:  Cardiology research and practice     Volume:  2011     ISSN:  2090-0597     ISO Abbreviation:  Cardiol Res Pract     Publication Date:  2011  
Date Detail:
Created Date:  2011-02-25     Completed Date:  2011-07-14     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101516542     Medline TA:  Cardiol Res Pract     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  578390     Citation Subset:  -    
Aintree Cardiac Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK.
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