Document Detail

Aggressive angiomyxoma of the vulva: case report and literature review.
MedLine Citation:
PMID:  20926030     Owner:  NLM     Status:  MEDLINE    
Aggressive angiomyxoma is a rare softtissue tumour, typically occurring in the female pelvis and carrying a high risk of local infiltration and relapse. Surgery remains the first line of treatment, however some adjuvant treatments, such as gonadotrophin-releasing hormone (GnRH) agonists, have been used for primary treatment and for treatment against tumour recurrence. We describe a case of vulvar aggressive angiomyxoma in a 31-year old woman who underwent surgical excision of the tumour. Diagnosis was made on the basis of histopathological examination and positive immunohistochemical staining with oestrogen and progesterone receptors. Postsurgery, a GnRH agonist (3.75 mg triptorelin) was injected intramuscularly every month for 3 months to prevent tumour recurrence and, to date, no relapse has been observed. Whether treatment is with surgery, hormone therapy or both, it is clear that aggressive angiomyxoma requires close, long-term follow-up to monitor for disease recurrence and that the individualization of each case is essential for adequate management.
N X Sun; W Li
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of international medical research     Volume:  38     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-10-07     Completed Date:  2010-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1547-52     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
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MeSH Terms
Myxoma / pathology*
Vulva / pathology
Vulvar Neoplasms / pathology*

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