Document Detail


Aggregation-disaggregation transition of DNA-coated colloids: experiments and theory.
MedLine Citation:
PMID:  20481724     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Colloids coated with complementary single-stranded DNA "sticky ends" associate and dissociate upon heating. Recently, microscopy experiments have been carried out where this association-dissociation transition has been investigated for different types of DNA and different DNA coverages [R. Dreyfus, M. E. Leunissen, R. Sha, A. V. Tkachenko, N. C. Seeman, D. J. Pine, and P. M. Chaikin, Phys. Rev. Lett. 102, 048301 (2009)]. It has been shown that this transition can be described by a simple quantitative model which takes into account the features of the tethered DNA on the particles and unravels the importance of an entropy cost due to DNA confinement between the surfaces. In this paper, we first present an extensive description of the experiments that were carried out. A step-by-step model is then developed starting from the level of statistical mechanics of tethered DNA to that of colloidal aggregates. This model is shown to describe the experiments with excellent agreement for the temperature and width of the transition, which are both essential properties for complex self-assembly processes.
Authors:
Rémi Dreyfus; Mirjam E Leunissen; Roujie Sha; Alexei Tkachenko; Nadrian C Seeman; David J Pine; Paul M Chaikin
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Publication Detail:
Type:  Journal Article     Date:  2010-04-23
Journal Detail:
Title:  Physical review. E, Statistical, nonlinear, and soft matter physics     Volume:  81     ISSN:  1550-2376     ISO Abbreviation:  Phys Rev E Stat Nonlin Soft Matter Phys     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-08-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136452     Medline TA:  Phys Rev E Stat Nonlin Soft Matter Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  041404     Citation Subset:  IM    
Affiliation:
Center for Soft Matter Research, New York University, New York, New York 10003, USA. remi.dreyfus@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Colloids
DNA / chemistry*
Engineering
Entropy
Hot Temperature
Kinetics
Models, Chemical*
Nucleic Acid Hybridization
Particle Size
Chemical
Reg. No./Substance:
0/Colloids; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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