Document Detail

Aggravating factors in the development of ocular abnormalities in farmed Atlantic halibut (Hippoglossus hippoglossus).
MedLine Citation:
PMID:  16309935     Owner:  NLM     Status:  MEDLINE    
Cystic lesions in the eyes of farmed halibut with a number of ocular sequelae have been reported previously with evidence that the condition can be associated with increased activity of choroidal carbonic anhydrase and elevated oxygen tension in the aqueous humour of affected fish. These changes may be compared to the 'bends' in human divers which are characterized by elevated circulating levels of nitrogen together with aggravating factors such as physical exercise. It is postulated that bubble formation and subsequent development of cysts in halibut require not only high aqueous humour oxygen tension but also the imposition of factors such as handling or intraspecific aggression which lead to bubble formation. A significantly higher incidence of lesions was noted in fish handled, weighed and measured every two weeks compared with a control group of unhandled fish, suggesting that physical activity associated with handled and possibly also intraspecific aggression is a factor in generation of ocular lesions in these fish.
D L Williams; W M Brancker
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Publication Detail:
Type:  Journal Article     Date:  2005-11-23
Journal Detail:
Title:  Veterinary journal (London, England : 1997)     Volume:  172     ISSN:  1090-0233     ISO Abbreviation:  Vet. J.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-24     Completed Date:  2007-01-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706281     Medline TA:  Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  501-5     Citation Subset:  IM    
Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, UK.
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MeSH Terms
Eye Diseases / etiology,  veterinary*
Fish Diseases / etiology*
Fisheries / methods
Random Allocation

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