Document Detail


Ageing in vivo and neuraminidase treatment of rabbit erythrocytes: influence on half-life as assessed by 51Cr labelling.
MedLine Citation:
PMID:  1150154     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Old and young rabbit erythrocytes, separated by centrifugation, contained different respective activities of glucose-6-phosphate dehydrogenase, pyruvate kinase and acetylcholinesterase, and different quantities of stromal sialic acid. A systematic study of the survival rate of young and old erythrocytes incubated with different amounts of Vibrio cholerae neuraminidase is described. The half-life of intact old erythrocytes is significantly shorter than that of young erythrocytes with a similar sialic acid content.
Authors:
L Gattegno; D Bladier; P Cornillot
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hoppe-Seyler's Zeitschrift für physiologische Chemie     Volume:  356     ISSN:  0018-4888     ISO Abbreviation:  Hoppe-Seyler's Z. Physiol. Chem.     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  2985060R     Medline TA:  Hoppe Seylers Z Physiol Chem     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  391-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Survival / drug effects
Cholinesterases / blood
Chromium Radioisotopes / diagnostic use
Erythrocyte Aging*
Erythrocytes / analysis,  drug effects*
Glucosephosphate Dehydrogenase / blood
Half-Life
Male
Neuraminidase / pharmacology*
Pyruvate Kinase / blood
Rabbits
Sialic Acids / blood
Vibrio cholerae / enzymology
Chemical
Reg. No./Substance:
0/Chromium Radioisotopes; 0/Sialic Acids; EC 1.1.1.49/Glucosephosphate Dehydrogenase; EC 2.7.1.40/Pyruvate Kinase; EC 3.1.1.8/Cholinesterases; EC 3.2.1.18/Neuraminidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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