Document Detail


Age- and sex-related effects on ankle-brachial index in a screened cohort of Japanese: the Okinawa Peripheral Arterial Disease Study (OPADS).
MedLine Citation:
PMID:  23033545     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aims: Age-related change of ankle-brachial index (ABI) within the general population, especially <40 years, has not been determined in large population studies. We evaluated the value of the ABI by age- and sex-related differences in a screened cohort.Methods and results: The ABI was examined in 13,211 participants (aged 21-89 years) in a health evaluation programme. The mean ABI was lower in women than in men at all ages. The ABI was lowest at <40 years, and increased with age; the maximum was at 60-69 years in both sexes. In participants <40 years, 186 (22%) of women and 108 (9.8%) of men had a borderline ABI (0.9-1.0). The prevalence of an ABI ≤0.9 in men increased with age, and sharply rose to 3.3% at ≥70 years. Conversely, women demonstrated a J-curve relationship, where the prevalence of an ABI ≤0.9 was lowest at 60-69 years (0.2%), and increased at <40 (0.9%) and ≥70 years (1.6%). The prevalence of atherosclerotic risk factors was higher in participants with an ABI ≤0.9 than those with an ABI >0.9 in men, both ≤60 and >60 years, and in women >60 years. In women ≤60 years, however, the prevalence of atherosclerotic risk factors in participants with an ABI >0.9 was as small as those with an ABI ≤0.9.Conclusion: The ABI increased with age until 60-69 years, and was lower in women than in men. It is unlikely that a low ABI in younger healthy women always indicate that existence of arterial stenosis.
Authors:
Akio Ishida; Megumi Miyagi; Kozen Kinjo; Yusuke Ohya
Related Documents :
18437125 - Risk factors associated with newly diagnosed high blood pressure in men and women.
24331135 - Obesity trends by ethnicity in hawai'i: the last ten years (1999-2008).
24682965 - Modifiable cardiovascular risk factors and axial motor impairments in parkinson disease.
23883635 - Sarcopenia and its risk factors in epidemiological study.
17957785 - Genetic polymorphisms of mdm2, cumulative cigarette smoking and nonsmall cell lung canc...
15741815 - A long-term prospective study of risk factors for glaucomatous visual field loss in pat...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-2
Journal Detail:
Title:  European journal of preventive cardiology     Volume:  -     ISSN:  2047-4881     ISO Abbreviation:  Eur J Prev Cardiol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101564430     Medline TA:  Eur J Prev Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
University of the Ryukyus, Okinawa, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Impact of Pharmacist Discharge Medication Therapy Counseling and Disease State Education: Pharmacist...
Next Document:  Initiation and maintenance of cardiovascular medications following cardiovascular risk assessment in...