| Age and sex differences in perioperative myocardial infarction after cardiac surgery. | |
| | |
MedLine Citation:
|
PMID: 22499802 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We investigate age and sex differences in acute myocardial infarction (AMI) after cardiac surgery in a prospective study of 2038 consecutive patients undergoing cardiac surgery with cardiopulmonary bypass. An age of ≥ 70 years implied changes in the type of AMI from the ST-segment elevation myocardial infarction (STEMI) to non-ST-segment elevation myocardial infarction (non-STEMI). Men were more likely than women to suffer from AMI after cardiac surgery (11.8% vs. 5.6%), as a result of the higher frequency of STEMI (6% of men vs. 1.8% of women; P < 0.001) in both age groups. A troponin-I (Tn-I) peak was significantly higher in patients ≥ 70 years old. In-hospital mortality was higher in patients ≥ 70 (7.3%) than in those < 70 years old (3.3%), because of the increased mortality observed in men with non-AMI (2.1% vs. 6.3%) and women with STEMI (0% vs. 28.6%) and non-STEMI (0% vs. 36.8%, P < 0.05). Old age was associated with a higher frequency of non-STEMI, Tn-I peak, mortality and length of stay in the intensive care unit (ICU). Regardless of age, men more often suffer from AMI (particularly STEMI). AMI in women had a notable impact on excess mortality and ICU stay observed in patients ≥ 70 years of age. Clinical and Tn-I peak differences are expected in relation to age and gender after AMI post-cardiac surgery. |
| | |
Authors:
|
Casimiro Javierre; Antoni Ricart; Rafael Manez; Elisabet Farrero; Maria L Carrio; David Rodriguez-Castro; Herminia Torrado; Josep L Ventura |
Publication Detail:
|
Type: Comparative Study; Journal Article Date: 2012-04-11 |
Journal Detail:
|
Title: Interactive cardiovascular and thoracic surgery Volume: 15 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-06-22 Completed Date: 2012-10-29 Revised Date: 2013-04-16 |
Medline Journal Info:
|
Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
|
Languages: eng Pagination: 28-32 Citation Subset: IM |
Affiliation:
|
Department of Physiological Sciences II, School of Medicine, University of Barcelona, IDIBELL, L'Hospitalet, Barcelona, Spain. cjavierre@ub.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Factors Aged Analysis of Variance Biological Markers / blood Cardiac Surgical Procedures / adverse effects*, mortality Cardiopulmonary Bypass / adverse effects Chi-Square Distribution Female Hospital Mortality Humans Incidence Intensive Care Units Length of Stay Male Myocardial Infarction / blood, etiology*, mortality Perioperative Period Prospective Studies Risk Assessment Risk Factors Sex Factors Spain Time Factors Troponin I / blood |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Troponin I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Surgical treatment for pulmonary aspergilloma: a 35-year experience in the Chinese population.
Next Document: Wide sternal retraction may impede internal mammary artery graft flow and reduce myocardial function...