Document Detail

Age related modifications of soluble proteins in various organs of male garden lizard, Calotes versicolor.
MedLine Citation:
PMID:  15374187     Owner:  NLM     Status:  PubMed-not-MEDLINE    
The oxidative modification of proteins measured as carbonyl derivatives increased with advancing age in the liver of male garden lizard. The same parameter did not show a significant change in other organs (brain, heart and kidney). Based on the observations in both homeotherms (mammals) and poikilotherms (insect and reptile), the in vivo oxidative modification of cellular proteins appears to be the most common mechanism leading to accumulation of altered proteins during aging. However, the degree of modifications may vary among the tissues/organs of a species. On the other hand the variations may also account for the role of modification of proteins in the pattern of aging in different species.
B S Jena; S Das; B K Patnaik
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of gerontology and geriatrics     Volume:  22     ISSN:  0167-4943     ISO Abbreviation:  Arch Gerontol Geriatr     Publication Date:    1996 Jan-Feb
Date Detail:
Created Date:  2004-09-17     Completed Date:  2005-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214379     Medline TA:  Arch Gerontol Geriatr     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  1-10     Citation Subset:  -    
Department of Zoology, Berhampur University, Berhampur - 760007, Orissa, India.
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