Document Detail


Age-related differences in enhancement and suppression of neural activity underlying selective attention in matched young and old adults.
MedLine Citation:
PMID:  23313874     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Selective attention reflects the top-down control of sensory processing that is mediated by enhancement or inhibition of neural activity. ERPs were used to investigate age-related differences in neural activity in an experiment examining selective attention to color under Attend and Ignore conditions, as well as under a Neutral condition in which color was task-irrelevant. We sought to determine whether differences in neural activity between old and young adult subjects were due to differences in age rather than executive capacity. Old subjects were matched to two groups of young subjects on the basis of neuropsychological test performance: one using age-appropriate norms and the other using test scores not adjusted for age. We found that old and young subject groups did not differ in the overall modulation of selective attention between Attend and Ignore conditions, as indexed by the size of the anterior Selection Positivity. However, in contrast to either young adult group, old subjects did not exhibit reduced neural activity under the Ignore relative to Neutral condition, but showed enhanced activity under the Attend condition. The onset and peak of the Selection Positivity occurred later for old than young subjects. In summary, older adults execute selective attention less efficiently than matched younger subjects, with slowed processing and failed suppression under Ignore. Increased enhancement under Attend may serve as a compensatory mechanism.
Authors:
A E Haring; T Y Zhuravleva; B R Alperin; D M Rentz; P J Holcomb; K R Daffner
Related Documents :
16291964 - Depletion of endogenous germ cells in male pigs and goats in preparation for germ cell ...
23538484 - Scottish country dance can benefit functional ability in older females.
20048194 - Vascular endothelial function is related to white blood cell count and myeloperoxidase ...
336214 - Sexual difference in lh-cells of the neonatal rats as revealed by immunocytochemistry.
16341854 - Development of reaching in infancy.
19166174 - Risk behaviours for hiv/aids infection among men who have sex with men in cairo, egypt.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2013-01-08
Journal Detail:
Title:  Brain research     Volume:  1499     ISSN:  1872-6240     ISO Abbreviation:  Brain Res.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-11     Completed Date:  2013-08-01     Revised Date:  2014-03-10    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  69-79     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier B.V. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Attention / physiology*
Brain / physiology*
Electroencephalography
Evoked Potentials / physiology*,  radiation effects*
Female
Humans
Male
Photic Stimulation
Reaction Time / physiology
Signal Processing, Computer-Assisted
Young Adult
Grant Support
ID/Acronym/Agency:
R01 AG017935/AG/NIA NIH HHS; R01AGO17935//PHS HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Flow behavior of fetal, neonatal and adult RBCs in narrow (3-6 ?m) capillaries - calculation and exp...
Next Document:  Orofacial sensory changes after streptozotocin-induced diabetes in rats.