Document Detail


Age-related differences in arterial compliance are independent of body mass index.
MedLine Citation:
PMID:  18388081     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study is to examine the effect of age on large and small arterial compliance in apparently healthy adults, and to determine whether this effect is independent of body mass index. The subjects consisted of 126 men and women, aged 45 years and above. The subjects rested supine while pulse contour analysis was measured from the radial artery to evaluate large and small arterial compliance. Large (12.0 +/- 4.2 mL/mm Hg x 10, mean +/- standard deviation) and small (3.3 +/- 1.9 mL/mm Hg x 100) arterial compliance were lower in the oldest group (P = .007, P = .002, respectively) compared with the youngest group (15.2 +/- 4.6 mL/mm Hg x 10 and 5.0 +/- 2.5 mL/mm Hg x 100, respectively). After adjusting for body mass index, large and small arterial compliance remained lower in the oldest group. Large and small arterial compliance are decreased with advancing age, independent of body mass index.
Authors:
Anette S Fjeldstad; Polly S Montgomery; Andrew W Gardner
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2008-04-02
Journal Detail:
Title:  Angiology     Volume:  59     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:    2008 Aug-Sep
Date Detail:
Created Date:  2008-08-22     Completed Date:  2008-09-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  454-8     Citation Subset:  IM    
Affiliation:
Department of Health and Exercise Sciences, University of Oklahoma, Norman, OK, USA.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Aging*
Blood Pressure
Body Mass Index
Compliance
Cross-Sectional Studies
Female
Humans
Hypertension / physiopathology*
Male
Middle Aged
Pulsatile Flow
Radial Artery / physiopathology*
Grant Support
ID/Acronym/Agency:
M01-RR-14467/RR/NCRR NIH HHS; R01-AG-16685/AG/NIA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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