| Age-related changes in normal adult pancreas: MR imaging evaluation. | |
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MedLine Citation:
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PMID: 21906894 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate age-related changes in normal adult pancreas as identified by magnetic resonance imaging (MRI). MATERIALS AND METHODS: We examined 115 patients without pancreatic diseases (21-90 years) who underwent upper abdominal MRI to evaluate the normal pancreatic MRI findings related to aging. The parameters examined were the pancreatic anteroposterior (AP) diameter, pancreatic lobulation, pancreatic signal intensity (SI), depiction of the main pancreatic duct (MPD), grade of the visual SI decrease on the opposed-phase T1-weighted images compared with in-phase images, and enhancement effect of the pancreas in the arterial phase of dynamic imaging. RESULTS: The pancreatic AP diameter significantly reduced (head, p=0.0172; body, p=0.0007; tail, p<0.0001), and lobulation (p<0.0001) and parenchymal fatty change (p<0.0001) became more evident with aging. No significant correlation was observed between aging and pancreatic SI, however the SI on the in-phase T1-weighted images tended to decrease with aging. No significant correlation was observed between aging and the depiction of the MPD as well as aging and contrast enhancement. CONCLUSION: MRI findings of pancreatic atrophy, lobulation, and fatty degeneration are characteristic changes related to aging, and it is necessary to recognize these changes in the interpretation of abdominal MRI in patients with and without pancreatic disease. |
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Authors:
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Tomohiro Sato; Katsuyoshi Ito; Tsutomu Tamada; Teruki Sone; Yasufumi Noda; Atsushi Higaki; Akihiko Kanki; Daigo Tanimoto; Hiroki Higashi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-7 |
Journal Detail:
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Title: European journal of radiology Volume: - ISSN: 1872-7727 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Radiology, Kawasaki Medical School, Matsushima, Kurashiki City, Okayama, 701-0192, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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