Document Detail

Age-related changes in motor unit function.
MedLine Citation:
PMID:  9149074     Owner:  NLM     Status:  MEDLINE    
This review focuses on the functional relationship between age-related morphological and physiological changes at the level of the motor unit (MU). It is well established that older humans are weaker than younger people, exhibit reduced force control, and have slower neuromuscular contractile properties. Older people may also exhibit a decrease in MU discharge rate, and an increase in variability of MU discharge at high force levels. The matching of MU discharge and contractile properties may be an age-related neurophysiological strategy adopted to optimize motor control, similar to that observed in acute conditions such as fatigue. Because muscle force output is modulated partially by MU discharge behavior, the study of these properties may offer insights into the physiology of muscular weakness and motor function in older people. In turn, this will allow the implementation of optimal exercise and rehabilitation programs to reduce the degree of dependence associated with aging.
M R Roos; C L Rice; A A Vandervoort
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Muscle & nerve     Volume:  20     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-06-05     Completed Date:  1997-06-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  679-90     Citation Subset:  IM    
Centre for Activity and Ageing, Faculty of Kinesiology, The University of Western Ontario, London, Canada.
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MeSH Terms
Aging / physiology*
Motor Neurons / physiology*
Muscle Fibers, Skeletal / physiology*

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