Document Detail

Age related changes in the distribution of laryngeal glands in the human adult larynx.
MedLine Citation:
PMID:  16580162     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To understand the defense status of glandular tissue in the human adult larynx, we examined the glandular distribution, concentration and the ratio of the mucous glands in the subglottic and supraglottic larynx. METHODS: One-hundred and seven adult larynges were examined. The area of the mucosa and glands were measured using an image analyzing system. The correlations of the concentration as well as the ratio of the mucous glands with age were analyzed. RESULTS: The ratio of the areas occupied by the glandular acini of the subglottis was almost equal to that of infants as we reported earlier. The concentration of the laryngeal glands decreased in higher-aged adults at the level of the supraglottis, but not at the level of the subglottis. CONCLUSIONS: In comparison to infants, the ratio of laryngeal glands of the human subglottic larynx is rather constant in human adults. However, the supraglottic larynx seems to be influenced by increasing age. The changes deserved in the laryngeal glands predominantly occur in the supraglottic larynx.
Hideichiro Tomita; Tadashi Nakashima; Akiteru Maeda; Hirohito Umeno; Kiminori Sato
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-03-31
Journal Detail:
Title:  Auris, nasus, larynx     Volume:  33     ISSN:  0385-8146     ISO Abbreviation:  Auris Nasus Larynx     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-06-19     Completed Date:  2008-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708170     Medline TA:  Auris Nasus Larynx     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  289-94     Citation Subset:  IM    
Department of Otolaryngology - Head and Neck Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
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MeSH Terms
Aged, 80 and over
Aging / pathology*,  physiology
Exocrine Glands / anatomy & histology*,  secretion
Image Processing, Computer-Assisted
Laryngeal Mucosa / anatomy & histology,  growth & development,  pathology*
Middle Aged
Mucus* / secretion
Regression Analysis
Tobacco / adverse effects

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