Document Detail

Age-related changes in the avian primary lymphoid organs (thymus and bursa of Fabricius).
MedLine Citation:
PMID:  14635141     Owner:  NLM     Status:  MEDLINE    
The avian primary lymphoid organs, the thymus and the bursa of Fabricius, undergo age-dependent changes leading in some cases to the complete atrophy of the organ. Nevertheless, the timetable of the involutive process as well as the consequences in the structure and functionality of the organs vary largely in the time frame and structural changes among species. On the other hand, and in contrast with the large body of literature reporting the structural and functional changes in mammalian primary lymphoid organs, the age-dependent changes in avian thymus and bursa of Fabricius are scarce, fragmentary, and heterogeneous. This article reviews the current literature on this topic, and focuses primarily on the involution of the bursa of Fabricius.
Emilia Ciriaco; Pablo P Píñera; Belén Díaz-Esnal; Rosaria Laurà
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Microscopy research and technique     Volume:  62     ISSN:  1059-910X     ISO Abbreviation:  Microsc. Res. Tech.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-11-24     Completed Date:  2004-02-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203012     Medline TA:  Microsc Res Tech     Country:  United States    
Other Details:
Languages:  eng     Pagination:  482-7     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley-Liss, Inc.
Dipartimento di Morfologia, Biochimica, Fisiologia e Produzioni Animali, Università di Messina, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aging / immunology*
Bursa of Fabricius / ultrastructure*
Columbidae / anatomy & histology,  immunology*,  physiology*
Thymus Gland / ultrastructure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Aging of the vertebrate immune system.
Next Document:  Thymic epithelial cells in age-dependent involution.