Document Detail

Age and lean body weight related growth curves of kidneys using real-time 3-dimensional ultrasound in pediatric urology.
MedLine Citation:
PMID:  15540774     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Kidney volume and growth are important parameters for evaluating and monitoring several diseases in pediatric urology. Studies have shown the significant relationship of kidney volume and function. Until now normal values of kidney size and growth have been based on 2-dimensional measurements combined with arithmetic formulas for the ellipsoid. Real-time 3-dimensional (RT3D) ultrasound is a new imaging modality. Moreover, corresponding software allows RT3D imaging within a short time exposure. We created nomograms of kidney volumes for routine diagnostics that could serve as a standard for pediatric renal growth assessment, decreasing the need for invasive tests. MATERIALS AND METHODS: RT3D volumetry of a total of 620 kidneys in 310 children with a homogeneous age distribution (range newborn to 10 years) and without any evidence of renal impairment was performed using a Voluson 730 (Kretztechnik, Ultrasound, Zipf, Austria) system. Polynomial regression analysis was applied for the prediction and estimation of growth variables of kidney volumes as a function of gender, age, body mass index or lean body weight. RESULTS: Stepwise multiple regression analysis incorporating the different independent variables indicated with significant correlation that age and lean body weight were the strongest predictors of kidney volumes in children. CONCLUSIONS: This study shows that RT3D ultrasound is particularly qualified for evaluating kidney volume in pediatric urology. RT3D volumetry is suitable for monitoring renal growth, reflecting kidney function. Furthermore, this methodology is feasible in screening programs assessing congenital urogenital diseases.
Josef Oswald; Christian Schwentner; Andreas Lunacek; Martina Deibl; Georg Bartsch; Christian Radmayr
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  172     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-15     Completed Date:  2005-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1991-4     Citation Subset:  AIM; IM    
Department of Pediatric Urology, University of Innsbruck, Innsbruck, Austria.
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MeSH Terms
Age Factors
Body Weight*
Child, Preschool
Computer Systems
Imaging, Three-Dimensional*
Infant, Newborn
Kidney / growth & development*,  ultrasonography*
Regression Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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