| Age of the female partner is a prognostic factor in prolonged unexplained infertility: a multicenter study. | |
MedLine Citation:
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PMID: 2526029 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Among 2,106 couples registered in 12 Canadian infertility clinics, 470 (22.3%) were classed as unexplained infertility after a uniform evaluation of the male ejaculate, ovulation, and tubal patency. The unexplained group included more older female partners; 44% were over 30 years of age at registration in the participating clinics, compared with 36% in other infertility diagnostic groups. The mean duration of infertility was 40.1 months, and the cumulative pregnancy rate was 36.6 +/- 2.9% at 2 years after registration. When the variables were examined with the use of proportional hazards analysis, each additional month of duration of infertility reduced the expected prognosis by 2%, and a history of pregnancy in the partnership improved the prognosis by 80%. Among couples with 3 years or more duration of infertility (cumulative pregnancy rate, 27.5 +/- 3.9%), an additional year in the age of the female partner when conception was first attempted (mean, 26.8 years) reduces the prognosis by 9%. |
Authors:
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J A Collins; T C Rowe |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Fertility and sterility Volume: 52 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1989 Jul |
Date Detail:
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Created Date: 1989-08-14 Completed Date: 1989-08-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 15-20 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors* Female Humans Infertility / etiology*, therapy Laparoscopy Male Multicenter Studies as Topic Pregnancy Prognosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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