Document Detail


Age of the female partner is a prognostic factor in prolonged unexplained infertility: a multicenter study.
MedLine Citation:
PMID:  2526029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Among 2,106 couples registered in 12 Canadian infertility clinics, 470 (22.3%) were classed as unexplained infertility after a uniform evaluation of the male ejaculate, ovulation, and tubal patency. The unexplained group included more older female partners; 44% were over 30 years of age at registration in the participating clinics, compared with 36% in other infertility diagnostic groups. The mean duration of infertility was 40.1 months, and the cumulative pregnancy rate was 36.6 +/- 2.9% at 2 years after registration. When the variables were examined with the use of proportional hazards analysis, each additional month of duration of infertility reduced the expected prognosis by 2%, and a history of pregnancy in the partnership improved the prognosis by 80%. Among couples with 3 years or more duration of infertility (cumulative pregnancy rate, 27.5 +/- 3.9%), an additional year in the age of the female partner when conception was first attempted (mean, 26.8 years) reduces the prognosis by 9%.
Authors:
J A Collins; T C Rowe
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Fertility and sterility     Volume:  52     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-08-14     Completed Date:  1989-08-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  15-20     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors*
Female
Humans
Infertility / etiology*,  therapy
Laparoscopy
Male
Multicenter Studies as Topic
Pregnancy
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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