| AGE AND DOSE-LIMITED PET-CT SCAN REGIME IN LYMPHOMA: BETWEEN THE DEVIL AND THE DEEP BLUE SEA? | |
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MedLine Citation:
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PMID: 22069232 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In this study the authors speculate about hypothetical effective-dose (E) reduction through limiting post-chemotherapy PET-CT scanning to lymphoma sites previously identified on pre-treatment CT. E reductions/scan time savings are compared between post-treatment standard and theoretically limited PET-CT scans. The influence of patient age with E savings and associated clinical implication for 100 subjects are discussed. The greatest E theoretical savings of 52 and 32 % for the CT contribution and combined PET-CT, respectively, were seen in patients <18 y old using limited scans in this study, with a potential mean time saving of 16 min per patient across the entire cohort. However, the limited PET-CT regime here missed a 1 % rate of unexpected cancer that standard PET-CT recorded. The authors recommend performing larger scale multi-centre studies comparing PET-CT pre- and post-chemotherapy to establish full clinical efficacy of this method. |
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Authors:
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B Sanghera; L I Sonoda; J Hart; G Vivian; T Mills; W L Wong |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-7 |
Journal Detail:
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Title: Radiation protection dosimetry Volume: - ISSN: 1742-3406 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8109958 Medline TA: Radiat Prot Dosimetry Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex HA6 2RN, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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