Document Detail

Age distribution of cases and deaths during the 1889 influenza pandemic.
MedLine Citation:
PMID:  21757106     Owner:  NLM     Status:  In-Data-Review    
Using historical data taken from archival records from five European countries and the United States, we evaluate the age distributions of influenza cases and deaths during the 1889 influenza pandemic. We found that the clinical attack rate in 1889 was relatively high and constant between the ages of 1 and 60 years, but was lower outside of the extremes of this age range. By contrast, age-specific influenza-related mortality rates were J-shaped and increased with age beyond 20 years. We conclude that the age-specific attack rates of the 1889 pandemic were most similar to those of the 1968 pandemic and that influenza-related mortality rates did not follow a W-shaped curve as was observed during the 1918 pandemic. Adding 1889 to the short catalogue of influenza pandemics previously studied makes the 1918 pandemic even more exceptional in terms of mortality burden and age distribution of deaths.
Sophie Valtat; Anne Cori; Fabrice Carrat; Alain-Jacques Valleron
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vaccine     Volume:  29 Suppl 2     ISSN:  1873-2518     ISO Abbreviation:  Vaccine     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406899     Medline TA:  Vaccine     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  B6-B10     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Institut National de la Santé et de la Recherche Médicale, U 707, F-75012 Paris, France; Université Pierre et Marie Curie-Paris 6, UMR-S 707, F-75012 Paris, France.
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