Document Detail

Age differences in within-session habituation of exploratory behavior: effects of stimulus complexity.
MedLine Citation:
PMID:  6508694     Owner:  NLM     Status:  MEDLINE    
The effects of age on the habituation of exploratory behavior of 8-month- and 28-month-old male C57BL/NNia mice were examined under three different stimulus complexity conditions. Increases in the degree of stimulus complexity resulted in an attenuation of between-session habituation and an initial disruption of within-session habituation by 8-month-old mice. Although increases in stimulus complexity also resulted in an increase in the overall level of exploration by aged mice, stimulus complexity was not found to have a systematic effect on between- or within-session habituation by aged mice. No between-session habituation was observed in aged mice under any of the stimulus complexity conditions. Further, aged mice exhibited significant within-session increases, rather than decreases, in exploration under each stimulus complexity condition. This disruption of within-session habituation in aged mice was found to persist over four daily test sessions. In view of the specific patterns of exploration by aged mice, the disruption of within-session habituation was attributed to age-related differences in reactivity to the arousal-inducing properties of novel stimuli.
M J Brennan; D Allen; D Aleman; E C Azmitia; D Quartermain
Related Documents :
19747234 - Hot topics in aging research: protein translation, 2009.
7830954 - Sex-related effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine treatment may be r...
20637274 - Kangen-karyu improves memory deficit caused by aging through normalization of neuro-pla...
21725834 - Characterization of fresh and aged natural ingredients used in historical ointments by ...
9008244 - 24-h ambulatory blood pressure monitoring in healthy young adult anglo, hispanic, and a...
7408914 - Puberty in laron type dwarfism.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Behavioral and neural biology     Volume:  42     ISSN:  0163-1047     ISO Abbreviation:  Behav. Neural Biol.     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1985-01-03     Completed Date:  1985-01-03     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7905471     Medline TA:  Behav Neural Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  61-72     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Exploratory Behavior*
Habituation, Psychophysiologic*
Mice, Inbred C57BL
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Neuropharmacological evidence to suggest that the nucleus accumbens and subpallidal region contribut...
Next Document:  Increased novelty-induced grooming in aged rats: a preliminary observation.