Document Detail

Age dependence of diffusion-weighted magnetic resonance imaging findings in maple syrup urine disease encephalopathy.
MedLine Citation:
PMID:  16012312     Owner:  NLM     Status:  MEDLINE    
A patient with maple syrup urine disease (MSUD) who developed encephalopathy twice and underwent magnetic resonance examinations, including diffusion-weighted (DW) imaging, is presented. Areas of abnormal intensity on DW images dramatically differed between the initial and second attacks, apparently attributable to the difference in myelination. Our observation demonstrates the age dependence of DW imaging findings in MSUD encephalopathy attributable to progression of myelination and would help in the proper diagnosis of MSUD encephalopathy at any age.
Mio Sakai; Yusuke Inoue; Hiroshi Oba; Akira Ishiguro; Kyoko Sekiguchi; Yoshihiko Tsukune; Masanori Mitomo; Hironobu Nakamura
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  29     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-07-13     Completed Date:  2005-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  524-7     Citation Subset:  IM    
Department of Radiology, Osaka National Hospital, Osaka 540-0006, Japan.
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MeSH Terms
Age Factors
Brain Diseases / etiology
Diffusion Magnetic Resonance Imaging
Disease Progression
Infant, Newborn
Maple Syrup Urine Disease / diagnosis,  pathology*

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