Document Detail


Age attenuated response to aerobic conditioning in postmenopausal women.
MedLine Citation:
PMID:  20397024     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The decline in aerobic capacity does not appear to be linear across age. To explore this relationship, we examined the maximal cardiorespiratory response of 251 postmenopausal women to 6 months of exercise training: control (no exercise), or exercise at 4, 8, or 12 kcal/kg/week (KKW). Exercise intensity was set at a heart rate associated with 50% of peak VO(2peak) and women were stratified by age into three groups: <55 years, 55-59 years, >60 years. Differences in outcomes among groups were tested by ANOVA and the results were presented as adjusted least squares means with confidence intervals. At baseline participants who were >60 years had a lower VO(2peak) than those <55 years [mean (SD) 1.44 (0.24) vs. 1.20 (0.20) L/min, P < 0.04). Following exercise training, we observed an attenuated training response due to age within the 8 and 12 KKW groups (both, P for trend 0.001). For the 8 KKW group, changes in VO(2peak) were [mean, (95% CI)]: <55 years [0.18 (0.12, 0.24) L/min], <55 years, 55-59 years [0.08 (0.02, 0.15) L/min], and >60 years [0.02 (-0.03, 0.08)]. For 12 KKW group, the changes were: <55 years [0.19 (0.15, 0.24) L/min], 55-59 years [0.13 (0.08, 0.18) L/min], and >60 years [0.05 (-0.01, 0.10)]. Our data show that despite similar exercise intensities, age plays a significant role in the maximal cardiorespiratory response to exercise training regardless of training volume in women who have completed menopause.
Authors:
Conrad P Earnest; Steven N Blair; Timothy S Church
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2010-04-16
Journal Detail:
Title:  European journal of applied physiology     Volume:  110     ISSN:  1439-6327     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-12     Completed Date:  2010-12-13     Revised Date:  2011-09-13    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  75-82     Citation Subset:  IM    
Affiliation:
Exercise Biology, Division of Preventive Medicine, Pennington Biomedical Research Center, Baton Rouge, LA, USA. conrad.earnest@pbrc.edu
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Analysis of Variance
Blood Pressure
Confidence Intervals
Exercise*
Exercise Tolerance
Female
Heart Rate
Humans
Least-Squares Analysis
Middle Aged
Obesity / physiopathology,  therapy*
Overweight / physiopathology,  therapy*
Oxygen Consumption
Physical Fitness*
Postmenopause*
Pulmonary Ventilation
Sedentary Lifestyle
Time Factors
Treatment Outcome
Grant Support
ID/Acronym/Agency:
HL66262/HL/NHLBI NIH HHS; R01 DK068298-05/DK/NIDDK NIH HHS
Comments/Corrections
Comment In:
Eur J Appl Physiol. 2011 May;111(5):891-2   [PMID:  20976467 ]

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