Document Detail


Age at menarche in juvenile rheumatoid arthritis.
MedLine Citation:
PMID:  12729405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the effect on the timing of menarche of the different subtypes of juvenile rheumatoid arthritis (JCA) and their therapies. METHODS: Auxological data (including the age at menarche of themselves and their mothers) were collected from 83 females regularly attending our rheumatological unit. Malnourished patients were excluded from the study. The patients were divided into groups on the basis of disease subtype and glucocorticoid (GC) therapy. RESULTS: The timing of menarche was later in all the patients in comparison with their mothers and normal Italian girls, and those who had taken GC had a later menarche and less pubertal growth than those who had not. The girls with systemic JCA had a later menarche than those with the polyarticular or pauciarticular subtypes. CONCLUSIONS: Our results show that pubertal development is compromised in girls with JCA, particularly if they have received GC therapy.
Authors:
Roberto Rusconi; Fabrizia Corona; Angela Grassi; Vittorio Carnelli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  16 Suppl 2     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-05-05     Completed Date:  2003-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  285-8     Citation Subset:  IM    
Affiliation:
Unit of Endocrinology, University of Milan, Italy. dnakr@tin.it
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Aging / physiology*
Arthritis, Juvenile Rheumatoid / drug therapy,  pathology,  physiopathology*
Body Height
Child
Female
Glucocorticoids / therapeutic use
Humans
Menarche*
Chemical
Reg. No./Substance:
0/Glucocorticoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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