Document Detail

Age alone is not a risk factor for left atrial thrombus in atrial fibrillation.
MedLine Citation:
PMID:  17591644     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Advanced age is an indication for anticoagulation in patients with atrial fibrillation though it is not clear that elderly patients have a higher prevalence of left atrial thrombus. The purpose of this study was to clarify whether advanced age represents a risk for left atrial thrombus formation irrespective of other clinical variables. DESIGN: Observational study in patients with atrial fibrillation undergoing a transoesophageal echo scan for various clinical indications. SETTING: University-affiliated cardiology service in a general hospital. PATIENTS: Results are reported in 381 patients, 257 aged less than 75 years (Gr. A) and 124 aged 75 years or more (Gr. B). RESULTS: Thrombi were detected by TOE in 30 patients (7.9%), 21 from group A and nine from group B (8.1% vs 7.2%, p = NS). No thrombi were detected in patients with lone atrial fibrillation. Among patients with either valvular or nonvalvular atrial fibrillation, left atrial thrombus presence was not related to age or anticoagulation status. CONCLUSIONS: In patients with atrial fibrillation, age itself does not predict the presence of left atrial thrombus and the only identifiable risk factor seems to be the existing cardiac pathology.
B Mazouz; A Keren; A Chenzbraun
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Publication Detail:
Type:  Journal Article     Date:  2007-06-25
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  94     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-15     Completed Date:  2008-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  197-9     Citation Subset:  AIM; IM    
The Heiden Department of Cardiology, Bikur Cholim Hospital, Jerusalem, Israel.
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MeSH Terms
Age Factors
Aged, 80 and over
Anticoagulants / therapeutic use
Atrial Fibrillation / complications*,  ultrasonography
Diabetic Angiopathies / complications
Echocardiography, Transesophageal
Heart Atria
Heart Diseases / etiology,  ultrasonography
Hypertension / complications
Middle Aged
Risk Factors
Stroke / complications
Thrombosis / etiology*,  prevention & control,  ultrasonography
Reg. No./Substance:

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