| Age and body mass index are independent risk factors for the development of postoperative paralytic ileus after radical cystectomy. | |
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MedLine Citation:
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PMID: 20472264 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To identify the risk factors that would aid in the identification of patients at the greatest risk of developing postoperative paralytic ileus (POI). POI is a common complication after radical cystectomy and can result in a prolonged hospital stay and delayed recovery. METHODS: A retrospective cohort study design was used to analyze data from consecutive patients presenting to our institution for radical cystectomy with pelvic nodal dissection. POI was declared if patients were without evidence of bowel function beyond the anticipated discharge goal of 6 days. The association between several clinical features and the occurrence of POI was examined. RESULTS: Of 283 patients, 43 (15.2%) developed POI. Of the 43 patients, 38 (88.4%) were given total parenteral nutrition for nutritional supplementation. No difference in the incidence of POI was observed between the sexes, previous abdominal operations, estimated blood loss, transfusion requirement, operative time, neoadjuvant chemotherapy, or previous radiotherapy. POI was observed in 11.3% of normal and overweight patients (body mass index [BMI] <30.0 kg/m(2)) compared with 25.6% of obese patients (BMI ≥30.0 kg/m(2); P = .005). On multivariate analysis adjusted for the influence of competing variables, increasing age (hazard ratio 1.09, 95% confidence interval 1.02-1.16, P = .008) and BMI (hazard ratio 1.09, 95% confidence interval 1.03-1.17, P = .007) were significantly associated with the presence of POI. CONCLUSIONS: Our results showed that increasing age and BMI were significantly associated with the presence of POI in patients undergoing radical cystectomy for bladder cancer. |
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Authors:
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Robert S Svatek; Mark B Fisher; Michael B Williams; Surena F Matin; Ashish M Kamat; H Barton Grossman; Graciela M Nogueras-González; Diana L Urbauer; Colin P Dinney |
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Publication Detail:
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Type: Journal Article Date: 2010-05-15 |
Journal Detail:
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Title: Urology Volume: 76 ISSN: 1527-9995 ISO Abbreviation: Urology Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-06 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0366151 Medline TA: Urology Country: United States |
Other Details:
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Languages: eng Pagination: 1419-24 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors* Aged Body Mass Index* Cohort Studies Cystectomy / methods* Female Humans Intestinal Pseudo-Obstruction / epidemiology*, etiology Lymph Node Excision Male Middle Aged Obesity / complications Parenteral Nutrition, Total Postoperative Complications / epidemiology*, etiology Retrospective Studies Risk Factors Urinary Bladder Neoplasms / complications, surgery Urinary Diversion |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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