Document Detail

Afterload assessment with or without central venous pressure: a preliminary clinical comparison.
MedLine Citation:
PMID:  21165775     Owner:  NLM     Status:  In-Process    
A clinical comparison, of two methods of afterload assessment, has been made. The first method, systemic vascular resistance index (SVR(i)), is based upon the traditional formula for afterload which utilizes central venous pressure (CVP), as well as cardiac index (C(i)), and mean arterial blood pressure (MAP). The second method, total systemic vascular resistance index (TSVR(i)), also uses MAP and C(i). However, TSVR(i) ignores the contribution of CVP. This preliminary examination, of 10 randomly-selected ICU patients, has shown a high degree of correlation (ranging from 90 to 100%) between SVR(i) and TSVR(i) (P < 0.0001). Furthermore, there was also a high degree of correlation (ranging from 94 to 100%) noted between the hour-to-hour change in SVR(i) with the hour-to-hour change in TSVR(i) (P < 0.0001). The results, of this pilot study, support the premise that the use of CVP may not always be necessary for afterload evaluation in the clinical setting. Minimally-invasive means of measuring both C(i) and MAP, without CVP, may be adequate for use in assessing afterload.
Glen Atlas; Jay Berger; Sunil Dhar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular engineering (Dordrecht, Netherlands)     Volume:  10     ISSN:  1573-6806     ISO Abbreviation:  Cardiovasc Eng     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101132083     Medline TA:  Cardiovasc Eng     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  246-52     Citation Subset:  IM    
Department of Anesthesiology, University of Medicine and Dentistry of NJ, Newark, NJ, USA.
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