| After superovulation-intrauterine insemination fails: the prognosis for treatment by gamete intrafallopian transfer/pronuclear stage transfer. | |
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MedLine Citation:
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PMID: 1740206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the prognosis for gamete intrafallopian transfer (GIFT)/pronuclear stage transfer (PROST) treatment after prior superovulation-intrauterine insemination (IUI). DESIGN: Matched, retrospective. SETTING: Outpatient university endocrine-infertility program. PATIENTS, PARTICIPANTS: One hundred forty-four women matched for infertility factors and age were studied according to the following three treatment groups: superovulation-IUI only, GIFT/PROST only, or GIFT/PROST after superovulation-IUI. MAIN OUTCOME MEASURES: Per cycle and cumulative pregnancy rates (PRs) were compared utilizing life table analysis. RESULTS: Cumulative PRs (0.408) for superovulation-IUI only were lower than initial (0.469) and cumulative (0.802) cycle fecundity of GIFT/PROST (P = 0.002). Per cycle and cumulative PRs did not differ between GIFT/PROST only versus GIFT/PROST after superovulation-IUI. CONCLUSIONS: Gamete intrafallopian transfer/PROST may be cost-effective when compared with superovulation-IUI. The prognosis for GIFT/PROST success is not negatively affected by earlier superovulation-IUI treatment failure. |
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Authors:
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D Robinson; C H Syrop; D G Hammitt |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 57 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1992 Mar |
Date Detail:
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Created Date: 1992-03-26 Completed Date: 1992-03-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 606-12 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, Iowa City 52242-1009. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Gamete Intrafallopian Transfer* Humans Infertility, Female / etiology Insemination, Artificial* Male Pregnancy Reproductive Techniques* Retrospective Studies Superovulation* Treatment Outcome Uterus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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