| After the FLUSH trial: a prospective observational study of lipiodol flushing as an innovative treatment for unexplained and endometriosis-related infertility. | |
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MedLine Citation:
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PMID: 16866789 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To assess the demographics, efficacy and safety of lipiodol flushing fertility treatment. DESIGN: Prospective observational study. SETTING: Secondary level care infertility clinic and radiology centre based in Auckland, New Zealand. POPULATION: The first cohort of 100 New Zealand women with infertility to undergo lipiodol flushing as an innovative fertility treatment. METHODS: Women received lipiodol flushing performed by a hysterosalpingogram technique and were followed up at 6 months. MAIN OUTCOME MEASURES: Clinical pregnancy at 6 months post-treatment; and live birth or ongoing pregnancy. RESULTS: The overall pregnancy rate was 30% and the live birth or ongoing pregnancy rate 27%. For women under 40 years old, a 32% pregnancy rate and a 25% live birth or ongoing pregnancy rate were seen in women with unexplained infertility, and a 50% pregnancy rate and a 47% live birth or ongoing pregnancy rate were seen in women with endometriosis. Of women aged 40 years and older, the pregnancy rate was 13% and the live birth or ongoing pregnancy rate was 13%. The pregnancy rates included those occurring after additional interventions, such as intrauterine insemination and in vitro fertilisation, accounting for 12 of the 30 pregnancies. There were no treatment complications. CONCLUSION: This study provides further evidence of the efficacy and safety of lipiodol flushing fertility treatment. |
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Authors:
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Kira Brent; Wendy E Hadden; Marianne Weston-Webb; Neil P Johnson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Australian & New Zealand journal of obstetrics & gynaecology Volume: 46 ISSN: 0004-8666 ISO Abbreviation: Aust N Z J Obstet Gynaecol Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-07-26 Completed Date: 2006-11-28 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0001027 Medline TA: Aust N Z J Obstet Gynaecol Country: Australia |
Other Details:
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Languages: eng Pagination: 293-7 Citation Subset: IM |
Affiliation:
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University of Auckland, Auckland, New Zealand. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cohort Studies Contrast Media / administration & dosage* Endometriosis / drug therapy* Fallopian Tube Diseases / drug therapy* Fallopian Tubes* Female Humans Hysterosalpingography Infertility, Female / drug therapy* Iodized Oil / administration & dosage* Irrigation Middle Aged Pregnancy Pregnancy Rate Prospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 8001-40-9/Iodized Oil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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