Document Detail

African swine fever.
MedLine Citation:
PMID:  19967933     Owner:  NLM     Status:  MEDLINE    
African swine fever (ASF) is a devastating haemorrhagic fever of pigs that causes up to 100% mortality, for which there is no vaccine. It is caused by a unique DNA virus that is maintained in an ancient cycle between warthogs and argasid ticks, making it the only known DNA arbovirus. ASF has a high potential for transboundary spread, and has twice been transported from Africa to other continents--Europe and subsequently the Caribbean and Brazil (1957, 1959) and the Caucasus (2007). It is also a devastating constraint for pig production in Africa. Research at Onderstepoort Veterinary Institute has made and is making important contributions to knowledge of this disease, focusing on the cycle in warthogs and tampans and transmission from that cycle to domestic pigs, resistance to its effects in domestic pigs, and the molecular genetic characterisation and epidemiology of the virus.
Mary-Louise Penrith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Onderstepoort journal of veterinary research     Volume:  76     ISSN:  0030-2465     ISO Abbreviation:  Onderstepoort J. Vet. Res.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-12-08     Completed Date:  2010-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401107     Medline TA:  Onderstepoort J Vet Res     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  IM    
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria.
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MeSH Terms
African Swine Fever / epidemiology,  prevention & control*,  transmission*
African Swine Fever Virus / genetics,  immunology,  pathogenicity
Animals, Domestic / virology
Animals, Wild / virology
Arachnid Vectors / virology
Disease Reservoirs / veterinary*,  virology
Ornithodoros / virology
Tick Control / methods
Viral Vaccines / administration & dosage*
Reg. No./Substance:
0/Viral Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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