Document Detail

Aflatoxin levels in common foods of South Western Uganda: a risk factor to hepatocellular carcinoma.
MedLine Citation:
PMID:  20030698     Owner:  NLM     Status:  MEDLINE    
Prolonged exposure to aflatoxins by humans and animals leads to adverse effects to the various body systems of affected individuals including death. Studies have linked aflatoxins to hepatocellular carcinoma (HCC). In Uganda, HCC is observed to be on increase in communities of South-Western Uganda. A cross-sectional study was therefore conducted in five districts of the region and 90 various food samples were collected for total aflatoxin determination. They included ground nuts, cassava, millet, sorghum flour and eshabwe sauce. The aflatoxin levels were determined using Vicam aflatest method. The results were compared with acceptable European Union aflatoxin levels. Aflatoxin levels in the food samples ranged from 0 to 55 ppb with a mean total aflatoxin level of 15.7 +/- 4.9 ppb. Eshabwe sauce had the highest mean total aflatoxin levels (18.6 +/- 2.4 ppb). Traditional methods of food processing in this study were found to be contributing risk factor of food contamination and hence the observed increased HCC cases and mortalities in the region.
D Kitya; G S Bbosa; E Mulogo
Related Documents :
19777908 - Biological strategies to counteract the effects of mycotoxins.
16229058 - Comparative acute and combinative toxicity of aflatoxin b1 and t-2 toxin in animals and...
2942448 - The mycoflora and some mycotoxins found in acha (digitaria exilis stapf) in plateau sta...
9384738 - Analysis of fumonisin b1 in rodent feed by ce with fluorescence detection of the fmoc d...
25456238 - Organic acid blend with pure botanical product treatment reduces escherichia coli and s...
19777908 - Biological strategies to counteract the effects of mycotoxins.
Publication Detail:
Type:  Journal Article     Date:  2009-12-17
Journal Detail:
Title:  European journal of cancer care     Volume:  19     ISSN:  1365-2354     ISO Abbreviation:  Eur J Cancer Care (Engl)     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-20     Completed Date:  2011-01-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301979     Medline TA:  Eur J Cancer Care (Engl)     Country:  England    
Other Details:
Languages:  eng     Pagination:  516-21     Citation Subset:  N    
Faculty of Medicine, Department of Surgery, Mbarara University of Science and Technology, Mbarara, Uganda.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aflatoxins / metabolism,  poisoning*
Carcinoma, Hepatocellular / epidemiology,  etiology*
Cross-Sectional Studies
Food Contamination*
Liver Neoplasms / epidemiology,  etiology*
Risk Factors
Uganda / epidemiology
Reg. No./Substance:
0/Aflatoxins; 0/Poisons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Anxiety and depression in cancer patients compared with the general population.
Next Document:  Management of chylous fistula as a complication of neck dissection: a 10-year retrospective review.