Document Detail

Aflatoxin and aflatoxicosis: V. The kinetic behaviour of dietary aflatoxins in colostrum drawn from cows postpartum.
MedLine Citation:
PMID:  3990769     Owner:  NLM     Status:  MEDLINE    
This work was conducted in order to study the kinetic behaviour of dietary aflatoxins in the colostrum of a pregnant cow exposed to contaminated feeds for a short period. In this study, two pregnant cows received a single dose of dietary aflatoxins in the form of rice powder contained 31.20 ppm aflatoxin B and 19.68 ppm aflatoxin G during the last stage of pregnancy, at about two weeks before parturition. Samples of colostrum were collected from dams and assayed for the presence of toxic metabolites as well as its conjugations by electrophoretic analysis. The results revealed that the intake of aflatoxins appeared in the colostrum postpartum as AFM1 and also AFB2a which is a non toxic metabolite. Moreover, it was found that the excreted metabolites including AFB2a were conjugated to the immunoglobulin protein fraction of the colostrum. The significance of the obtained results to the newborn calf are discussed.
A H Hafez; S E Megalla; M A Mohran; A Y Nassar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mycopathologia     Volume:  89     ISSN:  0301-486X     ISO Abbreviation:  Mycopathologia     Publication Date:  1985 Mar 
Date Detail:
Created Date:  1985-06-20     Completed Date:  1985-06-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505689     Medline TA:  Mycopathologia     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  161-4     Citation Subset:  IM    
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MeSH Terms
Aflatoxins / analysis,  metabolism*,  poisoning
Animal Feed
Cattle Diseases / chemically induced*,  metabolism
Colostrum / analysis,  metabolism*
Food Microbiology
Postpartum Period*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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