Document Detail


Aflatoxicol and aflatoxins B1 and M1 in eggs and tissues of laying hens consuming aflatoxin-contaminated feed.
MedLine Citation:
PMID:  6419214     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was undertaken to relate quantitatively the aflatoxin residue found in eggs and tissues to the aflatoxin intake via feed. Eighteen hens were fed an aflatoxin B1 (B1)-contaminated feed (8 micrograms/g) for 7 days, after which half the group was sacrificed; the remainder were sacrificed after an additional 7 days on an aflatoxin-free diet. Eggs were collected over the entire 14-day period. Aflatoxicol (R0), B1, or both were found in eggs and tissues (kidneys, liver, muscle, blood, and ova). Aflatoxin M1 (M1) (.04 to .1 ng/g) was found only in the kidneys. Levels of R0 and B1 were approximately the same in eggs, ova, kidneys, and liver. In eggs, the levels of R0 and B1 (.02 to .2 ng/g) increased steadily for 4 or 5 days, after which time the levels plateaued and then decreased after B1 withdrawal at the same rate as they had increased. At 7 days after withdrawal, only trace amounts of R0 (.01 ng/g) remained in eggs. All tissues, except blood, from hens sacrificed immediately before aflatoxin withdrawal contained R0 (.04 to .4 ng/g) or R0 and B1 (.04 to .8 ng/g). The R0 (.03 to .11 ng/g) was the only aflatoxin detected in muscle, and B1 (.05 to .07 ng/g) was the only aflatoxin in blood. Seven days after aflatoxin withdrawal, B1 (.08 ng/g) was found in one of nine livers and R0 (.01 to .04 ng/g) in eight of nine muscles analyzed, but no aflatoxins were found in any other tissues.
Authors:
M W Trucksess; L Stoloff; K Young; R D Wyatt; B L Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Poultry science     Volume:  62     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2176-82     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aflatoxin B1
Aflatoxin M1
Aflatoxins / administration & dosage,  analysis*
Animal Feed*
Animals
Carcinogens / analysis*
Chickens / metabolism*
Eggs / analysis*
Female
Food Contamination*
Organ Specificity
Tissue Distribution
Chemical
Reg. No./Substance:
0/Aflatoxins; 0/Carcinogens; 1162-65-8/Aflatoxin B1; 29611-03-8/aflatoxicol; 6795-23-9/Aflatoxin M1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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