| Affective syndromes, psychotic features, and prognosis. I. Depression. | |
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MedLine Citation:
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PMID: 2360858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Prognosis is an important issue among patients who have psychotic features and a depressive syndrome; some have outcomes that suggest diagnostic revisions to schizophrenia, and this has far-reaching implications for treatment. To explore this issue, we used biannual evaluations to follow up 103 such individuals for 5 years. Patients with Research Diagnostic Criteria schizoaffective disorder experienced substantially more morbidity of various sorts than did patients with Research Diagnostic Criteria psychotic major depression. Within the group with schizoaffective disorder, patients with the chronic subtype experienced more morbidity than did those with nonchronic schizoaffective disorder; the mainly affective--mainly schizophrenic distinction had less prognostic significance. Factors that predicted sustained delusions at the end of follow-up were exclusively historical and suggested a poor-outcome prototype patient who is single, was socially impaired as an adolescent, and has a history of schizophrenialike psychotic features temporarily dissociated from affective symptoms. |
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Authors:
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W Coryell; M Keller; P Lavori; J Endicott |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Archives of general psychiatry Volume: 47 ISSN: 0003-990X ISO Abbreviation: Arch. Gen. Psychiatry Publication Date: 1990 Jul |
Date Detail:
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Created Date: 1990-08-01 Completed Date: 1990-08-01 Revised Date: 2013-04-18 |
Medline Journal Info:
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Nlm Unique ID: 0372435 Medline TA: Arch Gen Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 651-7 Citation Subset: AIM; IM |
Affiliation:
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National Institute of Mental Health Collaborative Program on the Psychobiology of Depression-Clinical Studies, Bethesda, Md. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Bipolar Disorder / diagnosis, psychology Depressive Disorder / diagnosis*, psychology Educational Status Female Follow-Up Studies Hospitalization Humans Male Prognosis Psychiatric Status Rating Scales Psychotic Disorders / diagnosis*, psychology Recurrence Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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R01 MH025478/MH/NIMH NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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