Document Detail


Aetiology and management of chylothorax in adults.
MedLine Citation:
PMID:  17580118     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Though rare in incidence, chylothorax can lead to significant morbidity and mortality. Its occurrence corresponds to increased mortality following esophagectomy. Leakage of chyle and lymph leads to significant loss of essential proteins, immunoglobulins, fat, vitamins, electrolytes and water. The presence of chylomicrons and a triglyceride level >110 mg/dl in the aspirated pleural fluid confirms the diagnosis of chylothorax. Identifying the aetiology using different diagnostic tests is important in planning treatment. While therapeutic thoracentesis provides relief from respiratory symptoms, the nutritional deficiency will continue to persist or deteriorate unless definitive therapeutic measures are instituted to stop leakage of chyle into the pleural space. Definitive therapy consists of obliteration and prevention of recurrence of chylothorax. Aggressive surgical therapy is recommended for post-traumatic or post-surgical chylothorax.
Authors:
Sukumaran K Nair; Matus Petko; Martin P Hayward
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-06-18
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  32     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-10     Completed Date:  2007-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  362-9     Citation Subset:  IM    
Affiliation:
Department of Cardiothoracic Surgery, The Heart Hospital, University College London NHS Trust, 16-18 Westmoreland Street, London W1G 8PH, United Kingdom. suku50@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Algorithms
Cholesterol / analysis
Chyle / metabolism
Chylothorax / etiology,  therapy*
Humans
Lymphatic System / anatomy & histology
Pleural Effusion / metabolism
Prognosis
Thoracic Surgical Procedures / methods
Thorax / anatomy & histology
Chemical
Reg. No./Substance:
57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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