| Aetiology of icteric hepatitis and fulminant hepatic failure in children and the possible predisposition to hepatic failure by sickle cell disease. | |
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MedLine Citation:
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PMID: 2157327 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aetiological agents of acute icteric hepatitis and fulminant hepatic failure were investigated in 47 children less than 12 years of age presenting at our hospital during the period January to December 1987. Hepatitis A virus was the aetiological agent in 72%, hepatitis B virus in 11%, cytomegalovirus in 2% and non A non B in 15%. These results confirm the endemicity of these viruses in the Saudi population and that they can be contracted in early life and could lead to severe hepatitis. Three of the patients who had hepatitis A virus infection developed fulminant hepatic failure and two of them died. Two of the patients who developed fulminant hepatic failure were also suffering from sickle cell disease. This raises the question of a possible predisposition to hepatic failure in sickle cell disease upon infection with hepatitis A virus. |
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Authors:
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M D Yohannan; M Arif; S Ramia |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta paediatrica Scandinavica Volume: 79 ISSN: 0001-656X ISO Abbreviation: Acta Paediatr Scand Publication Date: 1990 Feb |
Date Detail:
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Created Date: 1990-05-09 Completed Date: 1990-05-09 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0000211 Medline TA: Acta Paediatr Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 201-5 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Anemia, Sickle Cell / complications* Child Child, Preschool Cytomegalovirus Infections / etiology Hepatic Encephalopathy / etiology* Hepatitis A / etiology Hepatitis B / etiology Hepatitis C / etiology Hepatitis, Viral, Human / etiology Humans Infant Jaundice / etiology Liver Diseases / etiology* Male |
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