| Aetiology Of Bacteraemia Among Adult Aids Patients Attending Lagos University Teaching Hospital (LUTH), Lagos, Nigeria. | |
| | |
MedLine Citation:
|
PMID: 19767904 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND: Bacteraemia is a relatively common event in HIV-infected patients, especially in late infection. Studies in Africa have shown that more than 23% of AIDS patients have bacteraemia but there is paucity of data from Nigeria. METHODS: Blood samples from 67 consecutive patients with AIDS attending the Lagos University Teaching Hospital between April and August 2000 were cultured. Temperature, ESR, Full blood count, and where possible CD4 counts were obtained. Socio-demographic details were also recorded. Thirty apparently healthy people were randomly selected from a low-risk population to act as non-AIDS controls. The Oxoid Signal Blood Culture System was used to investigate bacteraemia. Antibiotic sensitivity tests were carried out on all isolates. RESULTS: Twenty-two (33%) of the 67 AIDS patients were culture positive. Non-typhoidal Salmonella spp (45.5%), coagulase-negative staphylococci (22.7%) and Staphylococcus aureus (18.2%) were most commonly isolated. One isolate each of Klebsiella pneumoniae, Pseudomonas aeruginosa and Bacillus spp were identified. All bacteraemic patients had temperatures above 38oC and white blood cell counts ranged between 2,700 - 13, 500/mm3. There was a high rate of antibiotic resistance particularly to chloramphenicol, tetracyclines, cotrimoxazole and b-lactam antibiotics. However, most isolates were still susceptible to gentamicin and the fluoroquinolones. There was no significant difference in the socio-demographics of the bacteraemic AIDS and non-bacteraemic AIDS patients. CONCLUSION: Salmonella spp. were the most common aetiological agent of bacteraemia among AIDS patients seen at the Lagos University Teaching Hospital (LUTH), Nigeria. A high temperature was a pointer to the presence of bactaeraemia while total white blood cell counts were not useful. It is recommended that blood culture should be done for AIDS patients with elevated temperature irrespective of the total white blood cell count. |
| | |
Authors:
|
F T Ogunsola; D G Arewa; I E Akinsete; O O Oduyebo; A S Akanmu; T O Odugbemi |
Related Documents
:
|
1309154 - Csf in 85 patients with aids and cns cryptococcosis. 2843454 - Renal cytomembranous inclusions in idiopathic renal disease as predictive markers for t... 8879714 - The taps project. 36: the most difficult to place long-stay psychiatric in-patients. ou... 8816134 - Epidemiology of cryptococcosis in france: a 9-year survey (1985-1993). french cryptococ... 17461334 - Social networks and hiv/aids risk perceptions. 19363484 - Hoxc4 binds to the promoter of the cytidine deaminase aid gene to induce aid expression... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Nigerian postgraduate medical journal Volume: 16 ISSN: 1117-1936 ISO Abbreviation: Niger Postgrad Med J Publication Date: 2009 Sep |
Date Detail:
|
Created Date: 2009-09-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9613595 Medline TA: Niger Postgrad Med J Country: Nigeria |
Other Details:
|
Languages: eng Pagination: 186-92 Citation Subset: IM |
Affiliation:
|
Department of Medical Microbiology College of Medicine, University of Lagos, P.M.B 12003, Lagos Nigeria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Utility of Intradermal Blood Smear in the detection of Asymptomatic Malaria Parasitaemia in Pregnanc...
Next Document: Knowledge and self-perception of breath odour amongst house officers at the university college hospi...