| Aerobic vaginitis in pregnancy. | |
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MedLine Citation:
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PMID: 21668769 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Please cite this paper as: Donders G, Bellen G, Rezeberga D. Aerobic vaginitis in pregnancy. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03020.x. Aerobic vaginitis (AV) is an alteration in vaginal bacterial flora that differs from bacterial vaginosis (BV). AV is characterised by an abnormal vaginal microflora accompanied by an increased localised inflammatory reaction and immune response, as opposed to the suppressed immune response that is characteristic of BV. Given the increased local production of interleukin (IL)-1, IL-6 and IL-8 associated with AV during pregnancy, not surprisingly AV is associated with an increased risk of preterm delivery, chorioamnionitis and funisitis of the fetus. There is no consensus on the optimal treatment for AV in pregnant or non-pregnant women, but a broader spectrum drug such as clindamycin is preferred above metronidazole to prevent infection-related preterm birth. The exact role of AV in pregnancy, the potential benefit of screening, and the use of newer local antibiotics, disinfectants, probiotics and immune modulators need further study. |
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Authors:
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Ggg Donders; G Bellen; D Rezeberga |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-14 |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: - ISSN: 1471-0528 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2011 RCOG. |
Affiliation:
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Department of Obstetrics and Gynaecology, The Regional Hospital Heilig Hart Tienen and University Hospital Gasthuisberg Leuven, Belgium Femicare vzw, Clinical Research for Women, Tienen, Belgium Department of Obstetrics and Gynaecology, Riga Stradins University, Riga, Latvia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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