| Aerobic performance and antioxidant protection in runners. | |
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MedLine Citation:
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PMID: 19685417 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Reactive oxygen species (ROS) production is known to increase as a result of muscular contractile activity and this phenomenon may perturb the fine-controlled cellular redox homeostasis within cells and tissues. We studied the possible correlations between individual aerobic performance-related factors and the oxidative stress markers profile in the serum of thirty-five endurance male runners that experienced a modified Bruce-based maximal graded exercise test. Our investigation assessed the systemic levels of malondialdehyde (MDA), protein carbonyl content (PCC) and total antioxidant status (TAS). We found that redox-related parameters and aerobic performance indicators were correlated. Indeed, significant negative associations between TAS and PCC (r-value -0.7, p<0.001) and between TAS and total protein content (r-value -0.4, p=0.005) were observed. A significant positive association between total protein and PCC (r-value 0.4, p=0.012) was also revealed. Only a trend of negative correlation between serum total protein and anaerobic threshold (r-value -0.3, p=0.07) was found. Interestingly, different responses in MDA levels were elicited by the ergometric test as a function of the individual anaerobic threshold. High aerobic capacities may be promising anthropometric factors indicative of adapted biochemical environments featuring enhanced protection against the oxidative challenge elicited by both regular endurance training and single intense exercise bouts. |
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Authors:
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S Falone; A Mirabilio; A Passerini; P Izzicupo; M Cacchio; S Gallina; A Di Baldassarre; A D Baldassarre; F Amicarelli |
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Publication Detail:
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Type: Journal Article Date: 2009-08-14 |
Journal Detail:
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Title: International journal of sports medicine Volume: 30 ISSN: 1439-3964 ISO Abbreviation: Int J Sports Med Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-30 Completed Date: 2010-01-25 Revised Date: 2011-01-06 |
Medline Journal Info:
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Nlm Unique ID: 8008349 Medline TA: Int J Sports Med Country: Germany |
Other Details:
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Languages: eng Pagination: 782-8 Citation Subset: IM |
Copyright Information:
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(c) Georg Thieme Verlag KG Stuttgart . New York. |
Affiliation:
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University G. d'Annunzio, Department of Biomedical Sciences, Chieti, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anaerobic Threshold / physiology Antioxidants / metabolism* Blood Proteins / metabolism Ergometry Exercise Test Humans Male Malondialdehyde / metabolism Middle Aged Oxidation-Reduction Oxidative Stress / physiology* Protein Carbonylation / physiology Reactive Oxygen Species / metabolism* Running / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Blood Proteins; 0/Reactive Oxygen Species; 542-78-9/Malondialdehyde |
| Comments/Corrections | |
Erratum In:
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Int J Sports Med. 2010 Mar;31(3):219 Note: Baldassarre, A D [corrected to Baldassarre, A Di] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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