Document Detail


Aerobic exercise training reduces epicardial fat in obese men.
MedLine Citation:
PMID:  18927266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to determine the effects of exercise training on ventricular epicardial fat thickness in obese men and to investigate the relationship of the change in epicardial fat thickness to changes in abdominal fat tissue following exercise training. Twenty-four obese middle-aged men [age, 49.4 +/- 9.6 yr; weight, 87.7 +/- 11.2 kg; body mass index (BMI), 30.7 +/- 3.3 kg/m(2); peak oxygen consumption, 28.4 +/- 7.2 ml.kg(-1).min(-1); means +/- SD] participated in this study. Each participant completed a 12-wk supervised exercise training program (60-70% of the maximal heart rate; 60 min/day, 3 days/wk) and underwent a transthoracic echocardiography. The epicardial fat thickness on the free wall of the right ventricle was measured from both parasternal long- and short-axis views. The visceral adipose tissue (VAT) and subcutaneous adipose tissues were measured by computed tomography. Following exercise training, the epicardial fat thickness was significantly decreased (P < 0.001). The percentage change of epicardial fat thickness was twice as high compared with those of waist, BMI, and body weight of original values (P <0.05). There was a significant relationship (r = 0.525, P = 0.008) between changes in the epicardial fat thickness and VAT with exercise training. Stepwise multiple regression analysis revealed that the change in VAT, change in systolic blood pressure, and change in quantitative insulin sensitivity check index were independently related to the change epicardial fat thickness (P < 0.05). The ventricular epicardial fat thickness is reduced significantly after aerobic exercise training and is associated with a decrease in VAT. These results suggest that aerobic exercise training may be an effective nonpharmacological strategy for decreasing the ventricular epicardial fat thickness and visceral fat area in obese middle-aged men.
Authors:
Maeng-Kyu Kim; Tsugio Tomita; Mi-Ji Kim; Hiroyuki Sasai; Seiji Maeda; Kiyoji Tanaka
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-10-16
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  106     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-09     Completed Date:  2009-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5-11     Citation Subset:  IM    
Affiliation:
University of tsukuba, Tsukuba, Ibaraki, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / ultrasonography*
Adult
Blood Pressure
Body Mass Index
Body Weight
Exercise Therapy*
Heart Rate
Heart Ventricles / ultrasonography
Humans
Insulin Resistance
Intra-Abdominal Fat / radiography*
Male
Middle Aged
Obesity / physiopathology,  radiography,  therapy*,  ultrasonography
Oxygen Consumption
Pericardium / ultrasonography*
Subcutaneous Fat / radiography*
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Waist Circumference
Comments/Corrections
Comment In:
J Appl Physiol. 2009 Jan;106(1):1-2   [PMID:  18948441 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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