Document Detail

Aerobic exercise training programmes for improving physical and psychosocial health in adults with Down syndrome.
MedLine Citation:
PMID:  20464738     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although physical fitness has been suggested to improve physical and psychosocial health for a variety of population profiles, there is a lack of information about the safety and effectiveness of aerobic exercise for adults with Down syndrome.
OBJECTIVES: To evaluate the effectiveness and safety of aerobic exercise training programmes for physiological and psychosocial outcomes in adults with Down syndrome.
SEARCH STRATEGY: The following electronic databases were searched: The Cochrane Central Register of Controlled Trials (CENTRAL) (2009, Issue 1); MEDLINE (1966 to August 2009); EMBASE (1980 to August 2009); CINAHL (1982 to August 2009); LILACS (1982 to August 2009); PsycINFO (1887 to August 2009); ERIC (1966 to August 2009); Current Controlled Trials (August 2009); and Campbell Collaboration's Social, Psychological, Educational and Criminological Register (C2- SPECTR) (to August 2009). Information about ongoing clinical trials was sought by searching ( (accessed August 2009), and the National Research Register (NRR) (2009 Issue 1).
SELECTION CRITERIA: Randomised or quasi-randomised controlled trials using supervised aerobic exercise training programmes with behavioral components accepted as co-interventions.
DATA COLLECTION AND ANALYSIS: Two reviewers selected relevant trials, assessed methodological quality and extracted data. Where appropriate, data were pooled using meta-analysis with a random-effects model. Positive values favour the intervention group, while negative values favour the control group.
MAIN RESULTS: Three studies included in this systematic review used different kinds of aerobic activity: walking/jogging and rowing training and included participants with a broad age range (17 to 65 years). They were conducted in the USA, Portugal and Israel. In the meta-analyses, only maximal treadmill grade was improved after aerobic exercise training programmes (4.26 grades (%) [95% CI 2.06, 6.45]). Other variables relative to work performance that could not be combined in a meta-analysis were also improved in the intervention group (maximal test time P=0.0003), total turns of fan wheel (P=0.02), resistance of ergometer (p=0.003), power knee extension and flexion (p<0.00001), and timed up and go test (p=0.008). Thirty other outcomes measured in this review including, oxidative stress and body composition variables, could not be combined in the meta-analysis. Apart from work performance, trials reported no statistically significant improvements.
AUTHORS' CONCLUSIONS: There is insufficient evidence to demonstrate that there is improvement in physical or psychosocial outcomes of aerobic exercise in adults with Down syndrome. Although evidence exists to support improvements in physiological and psychological aspects from strategies using mixed physical activity programmes, well-conducted research examining long-term physical outcomes, adverse effects, psychosocial outcomes and costs is required before informed practice decisions can be made.
Régis B Andriolo; Regina P El Dib; Luis Ramos; Alvaro N Atallah; Edina Mk da Silva
Related Documents :
6737208 - Influence of aerobic exercise on depression.
10416998 - Comparison of short-term aerobic training and high aerobic power on tolerance to uncomp...
16034968 - Aerobic exercise training programmes for improving physical and psychosocial health in ...
1553398 - The effects of aerobic exercise on cardiovascular, facial emg, and self-report response...
22192598 - Non-uniform muscle adaptations to eccentric exercise and the implications for training ...
11691888 - The re-establishment of the normal blood lactate response to exercise in humans after p...
Publication Detail:
Type:  Journal Article; Meta-Analysis; Review     Date:  2010-05-12
Journal Detail:
Title:  The Cochrane database of systematic reviews     Volume:  -     ISSN:  1469-493X     ISO Abbreviation:  Cochrane Database Syst Rev     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-06-16     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  100909747     Medline TA:  Cochrane Database Syst Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  CD005176     Citation Subset:  IM    
Emergency Medicine and Evidence Based Medicine, Universidade Federal de São Paulo, Rua Pedro de Toledo 598, São Paulo, Brazil, 04039-001.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Down Syndrome / physiopathology*,  psychology*
Exercise* / physiology,  psychology
Middle Aged
Physical Fitness / physiology,  psychology
Program Evaluation
Randomized Controlled Trials as Topic
Young Adult
Update Of:
Cochrane Database Syst Rev. 2009;(3):CD005176   [PMID:  19588368 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Action plans with limited patient education only for exacerbations of chronic obstructive pulmonary ...
Next Document:  Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticost...