| Aequorin-expressing yeast emits light under electric control. | |
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MedLine Citation:
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PMID: 21291926 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In this study, we show the use of direct external electrical stimulation of a jellyfish luminescent calcium-activated protein, aequorin, expressed in a transgenic yeast strain. Yeast cultures were electrically stimulated through two electrodes coupled to a standard power generator. Even low (1.5V) electric pulses triggered a rapid light peak and serial light pulses were obtained after electric pulses were applied periodically, suggesting that the system is re-enacted after a short refraction time. These results open up a new scenario, in the very interphase between synthetic biology and cybernetics, in which complex cellular behavior might be subjected to electrical control. |
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Authors:
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Cristina Vilanova; Angeles Hueso; Carles Palanca; Guillem Marco; Miguel Pitarch; Eduardo Otero; Juny Crespo; Jerzy Szablowski; Sara Rivera; Laura Domínguez-Escribà; Emilio Navarro; Arnau Montagud; Pedro Fernández de Córdoba; Asier González; Joaquín Ariño; Andrés Moya; Javier Urchueguía; Manuel Porcar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-31 |
Journal Detail:
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Title: Journal of biotechnology Volume: - ISSN: 1873-4863 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-2-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8411927 Medline TA: J Biotechnol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier B.V. |
Affiliation:
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Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, Postal Code 22085, 46071 València, Spain; Interdisciplinary Modeling Group, Intertech, Instituto Universitario de Matemática Pura y Aplicada, IUMPA, Departamento de Matemática Aplicada, Universidad Politécnica de Valencia, Camino de Vera s/n, 46022 València, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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