| Advertising of prescription-only medicines to the public: does evidence of benefit counterbalance harm? | |
| | |
MedLine Citation:
|
PMID: 22429162 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Since the global withdrawal of rofecoxib (Vioxx) in 2004, concerns about public health effects of direct-to-consumer advertising (DTCA) have grown. A systematic review of the research evidence on behavioral, health, and cost effects, published in 2005, found four studies meeting inclusion criteria, which showed that DTCA increases prescribing volume and patient demand, and shifts prescribing. From 2005 to 2010, nine studies met similar criteria. These largely confirm previous results. Additional effects include a shift to less appropriate prescribing, differential effects by patient price sensitivity and drug type, switches to less cost-effective treatment, and sustained sales despite a price increase. Claimed effects on adherence do not stand up to scrutiny and are based mainly on negative trials. There is no evidence of improved treatment quality or early provision of needed care. If policy is to be informed by evidence, the strength of research methods and ability to assess causality need to be considered. |
| | |
Authors:
|
Barbara Mintzes |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Annual review of public health Volume: 33 ISSN: 1545-2093 ISO Abbreviation: Annu Rev Public Health Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-03-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8006431 Medline TA: Annu Rev Public Health Country: United States |
Other Details:
|
Languages: eng Pagination: 259-77 Citation Subset: IM |
Affiliation:
|
Therapeutics Initiative, Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3; email: barbara.mintzes@ti.ubc.ca. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Early intervention to reduce the global health and economic burden of major depression in older adul...
Next Document: Remodeling of ventricular repolarization in a chronic doxorubicin cardiotoxicity rat model.