| Adverse reactions to blood donations: the READ project. | |
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MedLine Citation:
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PMID: 20104279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: In 2006 in Italy 2,404,267 donations of blood components were made by 1,539,454 donors; approximately 55% of the donations were collected directly by Transfusion Structures (TS), while about 45% were collected in Donation Centres managed by Associations and Federations of Donors. The aim of the READ (Rilevamento Eventi Avversi alla Donazione) project is to create a network of TS to test a standardised system for monitoring adverse events (AE) related to blood donations. MATERIALS AND METHODS: Shared, standardised data collection forms, compatible with the forms produced by the ISBT-EHN, were prepared. Two types of form were used: (i) a form to collect data on single events (READ 1), to be used at the individual collection sites; (ii) a form for processing the data collected by each TS (READ 2). RESULTS: Between February and August 2008 six TS collected data related to the donation of 89,332 units of blood. Overall, 523 AE were recorded. The AE occurred in 0.59% of the donations. The mean duration of the symptoms was 17 minutes. Fifteen percent of the symptoms were related to the venipuncture (mainly haematomas) and 77% to vasovagal AE. The AE were defined severe (grade C) in 47 cases. The donations in which AE were recorded were completed in 81% of the cases; 59% of the AE did not require treatment. Three donors were monitored briefly (for less than 4 hours) in hospital. CONCLUSIONS: The use of standardised forms enabled the collection of data that could be analysed. Some problems related to the performance of the haemovigilance programme did, however, emerge: (i) organisational problems, (ii) limited sensitivity, (iii) inadequate training, and (iv) poorly defined responsibilities. These problems must be resolved at various levels: local, regional and national. |
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Authors:
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Giovanni Garozzo; Isabella Crocco; Barbara Giussani; Annalisa Martinucci; Stefano Monacelli; Vanda Randi |
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Publication Detail:
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Type: Journal Article; Multicenter Study |
Journal Detail:
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Title: Blood transfusion = Trasfusione del sangue Volume: 8 ISSN: 1723-2007 ISO Abbreviation: Blood Transfus Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-01-27 Completed Date: 2010-04-07 Revised Date: 2010-09-27 |
Medline Journal Info:
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Nlm Unique ID: 101237479 Medline TA: Blood Transfus Country: Italy |
Other Details:
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Languages: eng Pagination: 49-62 Citation Subset: IM |
Affiliation:
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SIMT Azienda Ospedaliera Ragusa, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Blood Donors* Female Hematoma / epidemiology*, etiology, prevention & control Humans Italy Male Middle Aged Phlebotomy / adverse effects* Syncope, Vasovagal / epidemiology*, etiology, prevention & control |
| Comments/Corrections | |
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