Document Detail

Adverse reactions of the skin to metoprolol and other beta-adrenoreceptor-blocking agents.
MedLine Citation:
PMID:  6113997     Owner:  NLM     Status:  MEDLINE    
Oral provocation tests revealed the relation between long-term oral use of metoprolol and development of psoriasiform and/or eczematous skin lesions in 3 patients. The clinical and histopathological findings in 1 case are described more in detail and are discussed. The data in the recent literature, with respect to side effects of skin due to different beta-blocking agents, are summarized. In addition, some aspects dealing with possible mechanism in the side effects of beta-blocking agents are briefly discussed. Since beta-blocking agents may cause similar side effects, as described during practolol treatment, on should still be alert to this possibility during long-term treatment with (new) beta-blocking agents, which may allow us to prevent serious damage that might occur in different organs.
H A Neumann; T van Joost
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatologica     Volume:  162     ISSN:  0011-9075     ISO Abbreviation:  Dermatologica     Publication Date:  1981  
Date Detail:
Created Date:  1981-09-25     Completed Date:  1981-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0211607     Medline TA:  Dermatologica     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  330-5     Citation Subset:  IM    
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MeSH Terms
Adrenergic beta-Antagonists / adverse effects*
Eczema / chemically induced
Fluorescent Antibody Technique
Metoprolol / adverse effects*
Middle Aged
Propanolamines / adverse effects*
Psoriasis / chemically induced
Skin Diseases / chemically induced*
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Propanolamines; 37350-58-6/Metoprolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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