Document Detail

Adverse reactions associated with norepinephrine in dental local anesthesia.
MedLine Citation:
PMID:  1308379     Owner:  NLM     Status:  MEDLINE    
Two cases are presented in which a 40-yr-old woman and a 20-yr-old woman developed severe headaches after injection of the local anesthetic Xylestesin-F (3% lidocaine with 1:25,000 norepinephrine). It is suggested that these severe headaches may have been associated with acute transient hypertensive episodes following injection of the local anesthetic. A review of the literature indicates that norepinephrine, at least at a concentration of 1:25,000, should be avoided because of its potential for cardiovascular disturbances.
P van der Bijl; A M Victor
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anesthesia progress     Volume:  39     ISSN:  0003-3006     ISO Abbreviation:  Anesth Prog     Publication Date:  1992  
Date Detail:
Created Date:  1993-09-24     Completed Date:  1993-09-24     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0043533     Medline TA:  Anesth Prog     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  87-9     Citation Subset:  D    
Department of Oral Medicine and Periodontics, Faculty of Dentistry, University of Stellenbosch, Tygerberg, South Africa.
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MeSH Terms
Anesthesia, Dental / adverse effects*
Anesthesia, Local / adverse effects*
Blood Pressure / drug effects
Drug Combinations
Headache / etiology*
Norepinephrine / adverse effects*
Vasoconstrictor Agents / adverse effects
Reg. No./Substance:
0/Drug Combinations; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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