Document Detail

Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis.
MedLine Citation:
PMID:  2822789     Owner:  NLM     Status:  MEDLINE    
In a patient with viral pneumonia, acute respiratory and renal failure and metabolic acidosis, a reduction in left ventricular stroke work was observed on the three occasions that 100 ml of 8.4% sodium bicarbonate was infused. Blood pressure and cardiac output decreased on two of the occasions. Since intravenous sodium bicarbonate may produce adverse cardiovascular effects, a right heart catheter should be inserted to monitor these effects when alkali therapy is administered to an acutely ill patient with metabolic acidosis.
D J Cooper; L I Worthley
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  13     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1987  
Date Detail:
Created Date:  1987-12-08     Completed Date:  1987-12-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  425-7     Citation Subset:  IM    
Department of Anaesthesia and Intensive Care, Royal Adelaide Hospital South Australia.
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MeSH Terms
Acidosis / drug therapy*,  physiopathology
Bicarbonates / adverse effects*
Heart Failure / chemically induced*,  physiopathology
Kidney Failure, Acute / complications
Pneumonia, Viral / complications
Sodium / adverse effects*
Sodium Bicarbonate
Reg. No./Substance:
0/Bicarbonates; 144-55-8/Sodium Bicarbonate; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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