| Adverse effect of pregnancy on melanoma: a reappraisal. | |
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MedLine Citation:
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PMID: 1247953 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of pregnancy on the prognosis of cutaneous melanoma in women of childbearing age was examined in a retrospective review of 251 surgically treated cases. There was no statistical difference in survival at five years, free of disease, for Stage I melanoma between nulliparous, parous nonpregnant, and pregnant women. For Stage II melanoma, however, a significantly lower survival rate was observed for pregnant patients (29%) and parous women who had experienced activation of the lesion in a previous pregnancy (22%), as compared with that of nulliparous patients (55%) and other patients in the parous group (51%); p less than 0.05. This discrepancy in survival, together with the observed higher frequencies of Stage II cases, melanomas occurring on the trunk, and symptoms such as bleeding, ulceration, irritation, and elevation of the lesion, strongly suggest an adverse influence of pregnancy on women with Stage II melanoma. |
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Authors:
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M H Shiu; D Schottenfeld; B Maclean; J G Fortner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cancer Volume: 37 ISSN: 0008-543X ISO Abbreviation: Cancer Publication Date: 1976 Jan |
Date Detail:
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Created Date: 1976-04-10 Completed Date: 1976-04-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0374236 Medline TA: Cancer Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 181-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Female Humans Melanoma / mortality*, pathology Middle Aged Parity Pregnancy Pregnancy Complications / mortality* Prognosis Skin Neoplasms / mortality*, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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